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      ],
      "referenceIds": [
        "casp:prediction-center",
        "ebi:miame-minseqe",
        "encode:data-standards",
        "gene-ontology:evidence-codes",
        "who:lab-biosafety-manual-4",
        "wwpdb:pdbx-mmcif"
      ],
      "crown": true
    },
    {
      "id": "structure-coordinate-evidence@1",
      "title": "Static structure-coordinate evidence",
      "stage": "measurement",
      "branch": "protein-folding",
      "summary": "Bind static structural coordinates to format, provenance, method context, quality metadata, and an explicit refusal to infer pathway or kinetics.",
      "prerequisites": [
        "biomolecule-context-provenance@1",
        "study-provenance-controls@1"
      ],
      "evidenceFloor": "LS2",
      "claimClass": "STATIC_STRUCTURE",
      "permittedConclusions": [
        "STATIC_STRUCTURE"
      ],
      "forbiddenConclusions": [
        "FOLDING_KINETICS",
        "FOLDING_PATHWAY"
      ],
      "artifactRequirements": [
        "A format-valid coordinate artifact digest with source, method class, and quality metadata.",
        "A bounded mapping from stable biomolecule context to the coordinate record.",
        "An explicit statement that static coordinates do not establish a folding pathway or kinetics."
      ],
      "revalidationTriggers": [
        "The coordinate record, source revision, quality metadata, method interpretation, or biomolecule mapping changes."
      ],
      "referenceIds": [
        "wwpdb:pdbx-mmcif"
      ],
      "crown": false
    },
    {
      "id": "study-provenance-controls@1",
      "title": "Study provenance, controls, and safety scope",
      "stage": "foundation",
      "branch": "biomolecule-foundations",
      "summary": "Freeze a GREEN-only question, prior evidence, denominator, controls, conflicts, safety exclusions, and bounded public metadata before analysis.",
      "prerequisites": [],
      "evidenceFloor": "LS0",
      "claimClass": "STUDY_PROVENANCE",
      "permittedConclusions": [
        "STUDY_PROVENANCE"
      ],
      "forbiddenConclusions": [],
      "artifactRequirements": [
        "A timestamped scope digest with declared question, denominator, exclusions, controls, conflicts, and stopping rules.",
        "A GREEN-only risk assessment that refuses every v0 RED topic and sends unknown risk to private metadata-only escalation.",
        "A public-artifact manifest containing synthetic or non-identifiable metadata only, with no sequence or operational protocol payload."
      ],
      "revalidationTriggers": [
        "The question, denominator, control plan, conflict graph, public-data class, or risk classification changes."
      ],
      "referenceIds": [
        "ebi:miame-minseqe",
        "encode:data-standards",
        "who:lab-biosafety-manual-4"
      ],
      "crown": false
    }
  ]
}
